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Mixed Carotenoids is a broad spectrum carotenoid supplement containing natural alpha- and beta-carotenes combined with lutein, lycopene, zeaxanthin and cryptoxanthin. All carotenoids have antioxidant activity, but their activities vary depending on which tissues they are deposited into preferentially. Mixed carotenoid supplements protect against imbalances caused by excessive intake of only one member of this diverse phytonutrient family.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
About Carotenoids
- Whereas beta-carotene has received more attention than other carotenoids, early research documenting the effects of high beta-carotene diets overlooked the fact that these diets were also high in other carotenoids (J Am Coll Nutr 1995;14:419-27).
- High doses of beta-carotene alone may reduce blood levels of other carotenoids (Am J Clin Nutr 2000; 71:950-5).
- All carotenoids have antioxidant activity, but some are deposited preferentially into specific body tissues, as in the affinity of lutein for the retina (Ann NY Acad Sci 1998;854:443-7; Int J Vitam Nutr Res 1998;68:349-53).
- Synthetic beta-carotene has failed to benefit health in several human clinical trials (Drug Saf 1999;21:253-66), whereas natural beta-carotene was studied in two trials with positive results (J Am Coll Nutr 1995;14:536 [abstr #48]; Ann Allergy Asthma Immunol 1999;82:549-53).
- Provitamin A carotenoids such as alpha- and beta-carotene represent excellent sources of vitamin A with no danger of vitamin A toxicity (Arch Biochem Biophys 2004;430:77-88).
- Lycopene, one of the most abundant carotenoids in the body, has been associated in human studies with optimum immune function (Proc Nutr Soc 1998;57:3A) and prostate health (Nutr Cancer 1999;33:159-64; Cancer Epidemiol Biomarkers Prev 2001;10:861-8).
- The xanthophylls, lutein and zeaxanthin, may play a special role in the health of the eyes; studies have found that their long-term intake appeared to support the health of the macula and the ocular lens (Optometry 2004;75:216-30; Nutrition 2003;19:21-4).
- Alpha-carotene and cryptoxanthin appear to confer preferential protection to lung tissue (J Natl Cancer Inst 1996;88:612-5; Cancer Epidemiol Biomarkers Prev 2001; 10:767-73).
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Supplement Information
- Recent large dietary studies have suggested that intake of several carotenoids is associated with more powerful protection for cellular health than is the intake of single members of the carotenoid family (Am J Epidemiol 2002;156:536-547; Cancer Epidemiol Biomarkers Prev 2000;9:357-365).
- Suggested use for adults: One capsule daily with meals, or as directed.
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